Projects, Principal Investigators and Applicants FOR 5046: Integrated analysis of epithelial SLC26 anion transporters – from molecular structure to pathophysiology Funding Period 2 Research Unit 5046 from 2024 onward Project Nr.ProjectPrinciple Investigator/ApplicantCoordination fundsProf. Dr. Dominik OliverP1Disorder-function relationships in SLC26 transportersProf. Dr. Eric GeertsmaP2Functional specialization of transporting and non-transporting SLC26 proteinsProf. Dr. Dominik OliverProf. Dr. Jan-Philipp MachtensP3Molecular composition and structure of the SLC26A5 microenvironment in sensory outer hair cellsProf. Dr. Dominik OliverP4Transport mechanisms and cellular functions of SLC26A11Prof. Dr. Mercedes Alfonso-PrietoProf. Dr. Christoph FahlkeDeciphering the transport metabolomes of SLC26A3, SLC26A6 and SLC26A9 in the human gastrointestinal tractProf. Dr. Ursula SeidlerP6The role of SLC26A2 in enteric and renal oxalate transportProf. Dr. Felix KnaufProf. Dr. Ute SchollP7Physiological significance of the interaction between SLC26A3 and SLC26A6 with CFTR or NHE3 for secretion and absorption in the intestineProf. Dr. Hans Georg LamprechtDr. Mahdi AmiriP8Physiological function and transport mode of the anion transporter SLC26A9 in the gastric and alveolar epitheliumProf. Dr. Ursula SeidlerPZNanobodies for multilevel examination of SLC26 transportersProf. Dr. Eric Geertsma